GO-DS21
Overview
The objective of this project is to study the impact of environmental (lifestyle, diet, sleep, physical activity, etc.) and genetic factors on the development of people with Down syndrome. More specifically, it is based on the observation that people with Down syndrome are more prone to metabolic disorders (overweight, for instance), endocrine (or hormonal), or behavioural disorders. The GO-DS21 project is interested in the link between these disorders and Down syndrome, in order to improve their diagnosis and treatment. The challenge is to prevent or minimise these disorders in order to improve the development and quality of life of people with Down syndrome.
Are you interested in taking part in this study?
Planned end date
31 Dec 2024 00:00Conditions
Down SyndromeInclusion Criteria
Down syndrome population:
1) Males and females aged 12 to 45 years.
2) With established genetic diagnosis of Down syndrome (full trisomy 21_ based on karyotype results - not exclusion if not available but will need to confirm karyotype before data analysis if not done previously).
3)Parent or legal guardian/representative and caregiver willing to give written informed consent, when necessary
4) Availability of parent/caregiver to accompany the subject to clinical visits. Subjects must be able/ willing to comply with procedures.
Exclusion Criteria
1) Comorbid conditions: Participation is allowed as long as health conditions are considered stable and will not
interfere with participation in the study.
2) Subjects with evidence of dementia or meeting clinical diagnoses for dementia.
3) Participation in a medication treatment trial in the last 3 months prior to the study, or in a similar study involving
completing the cognitive measures used in this project (to prevent learning effects).
4) Confirmed mosaic trisomy 21, partial trisomy 21, or translocation.